Pyloric Stenosis

What Is Pyloric Stenosis?

Pyloric stenosis is a condition in infants where the muscle at the lower end of the stomach—the pylorus—becomes abnormally thickened. This thickening blocks food from passing into the small intestine, leading to forceful vomiting and feeding difficulties. It typically develops in the first few weeks of life and is more common in boys than girls.

Causes and Risk Factors

The exact cause of pyloric stenosis is unknown, but several factors may contribute, including genetics and environmental triggers. It is not present at birth but usually develops in the first 3 to 6 weeks of life. Risk factors include:

  • Being male (especially first-born sons)
  • Family history of the condition
  • Use of certain antibiotics during infancy
  • Premature birth
  • Smoking during pregnancy

Signs and Symptoms

The hallmark symptom of pyloric stenosis is projectile vomiting—forceful, non-bilious vomiting that occurs shortly after feeding. Other signs may include:

  • Constant hunger
  • Weight loss or poor weight gain
  • Dehydration
  • Fewer wet diapers
  • Visible waves of stomach contractions (peristalsis)

Diagnosis

Doctors typically diagnose pyloric stenosis through a combination of physical examination and imaging tests. An ultrasound is the preferred diagnostic tool, revealing a thickened pyloric muscle. Blood tests may be used to evaluate dehydration or electrolyte imbalances caused by vomiting.

Treatment

The standard treatment for pyloric stenosis is a surgical procedure called pyloromyotomy. This minimally invasive surgery involves splitting the thickened muscle to allow normal passage of food into the small intestine. It is highly effective, and most infants recover quickly, with feedings resumed gradually within hours to days post-op.

Frequently Asked Questions

Pyloric stenosis typically appears between 3 and 6 weeks of age but can occur as early as 2 weeks or as late as 2 months.
If untreated, it can lead to severe dehydration and malnutrition. With prompt surgical treatment, the condition is curable and has excellent outcomes.
The procedure is called pyloromyotomy, and it’s often performed laparoscopically. It involves splitting the muscle to relieve the blockage.
Feeding usually resumes within 12–24 hours post-surgery, starting with small amounts and gradually increasing as tolerated.
Recurrence is extremely rare. Most babies recover fully and have no long-term issues.